N-nitrosoephedrine
N-nitrosoephedrine Basic information
- Product Name:
- N-nitrosoephedrine
- Synonyms:
-
- N-nitrosoephedrine
- N-Nitroso-α-pseudoephedrin
- NITROSOEPHEDRINE
- α-[1-(Methylnitrosoamino)ethyl]benzenemethanol
- α-[1-(N-Methyl-N-nitrosoamino)ethyl]benzyl alcohol
- 2-[Methyl(nitroso)amino]-1-phenylpropan-1-ol
- ZVTOLKAVCZXHFM-UHFFFAOYSA-N
- Benzenemethanol, α-[1-(methylnitrosoamino)ethyl]-
- CAS:
- 17608-59-2
- MF:
- C10H14N2O2
- MW:
- 194.23
- Mol File:
- 17608-59-2.mol
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N-nitrosoephedrine Chemical Properties
- Melting point:
- 89.7 °C
- Boiling point:
- 330.68°C (rough estimate)
- Density
- 1.1444 (rough estimate)
- refractive index
- 1.5000 (estimate)
- storage temp.
- 4°C, Inert atmosphere
- solubility
- Chloroform (Slightly), Dichloromethane (Slightly)
- form
- Oil
- pka
- 13.44±0.20(Predicted)
- color
- Pale Yellow
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N-nitrosoephedrine Usage And Synthesis
Uses
N-Nitrosoephedrine is an N-nitroso derivative of (1R,2S)-(-)-Ephedrine(E574995), which is a sympathomimetic amine commonly used to treat hypotension associated with anaesthesia. It is similar in molecular structure to the well-known drugs phenylpropanolamine. N-Nitrosoephedrine can be used for in-vivo formation of mutagenic N-nitroso compounds.
Safety Profile
Confirmed carcinogen. Poison by ingestion and intraperitoneal routes. An experimental teratogen. Mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.