2-chloro-3'-deoxyadenosine
2-chloro-3'-deoxyadenosine Basic information
- Product Name:
- 2-chloro-3'-deoxyadenosine
- Synonyms:
-
- 2-chloro-3'-deoxyadenosine
- (2R,3R,5S)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol
- Adenosine, 2-chloro-3'-deoxy-
- 2-Chloro-3’-deoxyadenosine
- CAS:
- 115044-75-2
- MF:
- C10H12ClN5O3
- MW:
- 285.69
- Mol File:
- 115044-75-2.mol
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2-chloro-3'-deoxyadenosine Usage And Synthesis
Uses
2-Chloro-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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