guanine 7-oxide
guanine 7-oxide Basic information
- Product Name:
- guanine 7-oxide
- Synonyms:
-
- guanine 7-oxide
- 2-Amino-1,9-dihydro-6H-purin-6-one 7-oxide
- 2-Amino-3,9-dihydro-6H-purin-6-one 7-oxide
- Antibiotic 3780
- 6H-Purin-6-one, 2-amino-1,9-dihydro-, 7-oxide
- CAS:
- 5227-68-9
- MF:
- C5H5N5O2
- MW:
- 167.13
- Mol File:
- 5227-68-9.mol
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guanine 7-oxide Chemical Properties
- Melting point:
- >300 °C
- Boiling point:
- 295.68°C (rough estimate)
- Density
- 1.5442 (rough estimate)
- refractive index
- 1.9000 (estimate)
- pka
- 12.63±0.20(Predicted)
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guanine 7-oxide Usage And Synthesis
Uses
Guanine-7-oxide (Guanine 7-N-oxide) is an antitumor antibiotic with anti-tumor, anti-Candida albicans activity, and can inhibit viral replication effect of herpes virus, infectious blood virus (IHNV), infectious pancreatic necrosis virus (IPNV) and so on. Guanine-7-oxide has good activity against mouse L1210 leukemia cells[1].
References
[1] D L Kern, et al. Guanine-7-oxide, a novel antitumor antibiotic. J Antibiot (Tokyo). 1985 May;38(5):572-4.