concanamycin G
concanamycin G Basic information
- Product Name:
- concanamycin G
- Synonyms:
-
- concanamycin G
- Oxacyclooctadeca-3,5,13,15-tetraen-2-one, 18-(2,8-dihydroxy-1,3,7-trimethyl-4-oxo-5,9-undecadienyl)-8,10-dihydroxy-3,17-dimethoxy-5,7,9,11,13-pentamethyl-, [7R-[3E,5E,7R*,8R*,9S*,10S*,11R*,13E,15E,17S*,18R*(1S*,2R*,3S*,5E,7S*,8R*,9E)]]- (9CI)
- CAS:
- 144730-82-5
- MF:
- C38H60O9
- MW:
- 660.88
- Mol File:
- 144730-82-5.mol
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concanamycin G Chemical Properties
- Boiling point:
- 816.4±65.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- pka
- 13.93±0.20(Predicted)
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concanamycin G Usage And Synthesis
Uses
Concanamycin G has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase (Ki=0.02 nM), which is an important tool for biochemical research[1].
References
[1] J T Woo, et al. Isolation, characterization and biological activities of concanamycins as inhibitors of lysosomal acidification. J Antibiot (Tokyo). 1992 Jul;45(7):1108-16. DOI:10.7164/antibiotics.45.1108