mixanpril
mixanpril Basic information
- Product Name:
- mixanpril
- Synonyms:
-
- mixanpril
- L-Alanine, N-[(2S,3R)-2-[(benzoylthio)methyl]-1-oxo-3-phenylbutyl]-
- CAS:
- 156039-69-9
- MF:
- C21H23NO4S
- MW:
- 385.48
- Mol File:
- 156039-69-9.mol
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mixanpril Usage And Synthesis
Description
Mixanpril is a lipophilic prodrug of RB 105.
Uses
Mixanpril is a compound with the ability to modulate insulin sensitivity and has the activity of regulating insulin sensitivity and femoral blood flow in obese Zucker rats. Mixanpril can affect insulin-mediated glucose disposal in obese Zucker rats and also has a regulatory effect on femoral blood flow, with different effects compared to the ACE inhibitor captopril.
References
[1] Effects of dual angiotensin-converting enzyme and neutral endopeptidase 24-11 chronic inhibition by mixanpril on insulin sensitivity in lean and obese Zucker rats DOI:10.1097/00005344-200302000-00015