A 83016F
A 83016F Basic information
- Product Name:
- A 83016F
- Synonyms:
-
- A 83016F
- 2,4,6-Heptatrienoic acid, 7-[tetrahydro-3-hydroxy-5-[2-methoxy-1,3-dimethyl-7-[[1-oxo-2-[tetrahydro-2,3,4-trihydroxy-5,5-dimethyl-6-(1,3-pentadienyl)-2H-pyran-2-yl]butyl]amino]-3,5-heptadienyl]-2-furanyl]-, [2R-[2α,2[S*[1S*[2R*(2E,4E,6E),3R*,5R*],2S*,3E,5E]],3β,4β,6β(1E,3Z)]]- (9CI)
- CAS:
- 142435-72-1
- MF:
- C37H55NO10
- MW:
- 673.8333
- Mol File:
- 142435-72-1.mol
A 83016F Chemical Properties
- Boiling point:
- 854.7±65.0 °C(Predicted)
- Density
- 1.212±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble
- form
- A solid
- pka
- 4.33±0.10(Predicted)
A 83016F Usage And Synthesis
Description
A-83016F is an aurodox antibiotic isolated from the actinomycete species A83016. It has weak activity against S. pneumoniae PARK, S. pyogenes, and H. influenzae with MIC values of 16, 32, and 64 μg/ml, respectively, in a broth dilution assay.
Uses
A 83016F is an unusual polyene originally isolated from an unidentified actinomycete and reported in 1992. Structurally, A 83016F is related to the phenelfamycins. A 83016F exhibits activity against Gram positive bacteria.
Uses
A 83016F is a unusual polyene originally isolated from an unidentified actinomycete and reported in 1992. Structurally, A 83016F is related to the phenelfamycins. A 83016F exhibits activity against Gram positive bacteria.
References
[1] T A SMITKA. A83016F, a new member of the aurodox family.[J]. Journal of Antibiotics, 1992, 45 4: 433-443. DOI: 10.7164/antibiotics.45.433
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