PD 121373
PD 121373 Basic information
- Product Name:
- PD 121373
- Synonyms:
-
- PD 121373
- 5-[(2-Aminoethyl)amino]-2-[2-(diethylamino)ethyl]-2H-[1]benzothiopyrano[4,3,2-cd]indazol-9-ol
- 2H-[1]Benzothiopyrano[4,3,2-cd]indazol-9-ol, 5-[(2-aminoethyl)amino]-2-[2-(diethylamino)ethyl]-
- CAS:
- 113457-06-0
- MF:
- C21H27N5OS
- MW:
- 397.54
- Mol File:
- 113457-06-0.mol
More
Less
PD 121373 Chemical Properties
- Boiling point:
- 643.7±55.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- pka
- 8.78±0.20(Predicted)
More
Less
PD 121373 Usage And Synthesis
Description
PD 121373 is a Benzothiopyrano-indazole cpd. The benzothiopyranoindazoles are potent inhibitors of nucleic acid synthesis, reducing both DNA and RNA synthesis to the same extent at similar concentrations. Like other known intercalators, these compounds produced DNA single- and double-strand breaks in a time- and concentration-dependent manner in L1210 cells.