Basic information Safety Supplier Related

TBS-COREY LACTONE ALDEHYDE

Basic information Safety Supplier Related

TBS-COREY LACTONE ALDEHYDE Basic information

Product Name:
TBS-COREY LACTONE ALDEHYDE
Synonyms:
  • [3AR-(3A-ALPHA,4BETA,5ALPHA,6A-ALPHA)]-5-(TERT-BUTYL-DIMETHYLSILYL) HEXAHYDRO-2-OXO-2H-CYCLOPENTA[B]FURAN-4-CARBOXALDEHYDE
  • 2H-Cyclopenta[b]furan-4-carboxaldehyde,5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]hexahydro-2-oxo-, [3aR-(3aa,4a,5b,6aa)]- (9CI)
  • TBS-COREY LACTONE ALDEHYDE
  • 2H-Cyclopenta[b]furan-4-carboxaldehyde, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]hexahydro-2-oxo-, (3aR,4R,5R,6aS)-
  • (3Ar,4R,5R,6As)-5-((Tert-Butyldimethylsilyl)Oxy)-2-Oxohexahydro-2H-Cyclopenta[B]Furan-4-Carbaldehyde
CAS:
64091-14-1
MF:
C14H24O4Si
MW:
284.42
Mol File:
64091-14-1.mol
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TBS-COREY LACTONE ALDEHYDE Chemical Properties

solubility 
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:2): .05 mg/ml; DMSO: 20 mg/ml; Ethanol: 25 mg/ml
form 
A crystalline solid
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TBS-COREY LACTONE ALDEHYDE Usage And Synthesis

Description

TBS-Corey lactone aldehyde is a versatile, hydroxyl-protected intermediate for the synthesis of prostaglandins and prostaglandin analogs. Prostaglandin derivatives with modifications in the alpha chain, the omega chain, or both, are readily accessible from TBS-Corey aldehyde.1

Definition

ChEBI: TBS-Corey Lactone Aldehyde is a gamma-lactone.

References

1. Bindra, J.S., and Bindra, R. Prostaglandin Synthesis ,(1977).

TBS-COREY LACTONE ALDEHYDESupplier

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