S 2720
S 2720 Basic information
- Product Name:
- S 2720
- Synonyms:
-
- S 2720
- prop-1-en-2-yl 7-chloro-2,2-dimethyl-3-sulfanylidene-4H-quinoxaline-1-carboxylate
- CAS:
- 146739-86-8
- MF:
- C14H15ClN2O2S
- MW:
- 310.7991
- Mol File:
- 146739-86-8.mol
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S 2720 Usage And Synthesis
Description
S 2720 is a human immunodeficiency virus type 1 (HIV-1)-specific reverse transcriptase (RT) inhibitor quinoxaline.
Uses
S-2720 is a potent inhibitor of both immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) and HIV-1 replication. The binding sites of S-2720 and the nonnucleoside compounds overlap. The small pocket in the p66 subunit-BI-RG-587 (HY-10570) complex is most likely the target of S-2720. S-2720 is a quinoxaline derivative, which is promising for research of HIV-1 infection[1].
References
[1] Kleim JP, et al. Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication. Antimicrob Agents Chemother. 1993 Aug;37(8):1659-64. DOI:10.1128/AAC.37.8.1659