Basic information Safety Supplier Related

SULINDAC SULFIDE

Basic information Safety Supplier Related

SULINDAC SULFIDE Basic information

Product Name:
SULINDAC SULFIDE
Synonyms:
  • (Z)-5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid
  • (Z)-5-FLUORO-2-METHYL-1-(4-METHYLTHIOBENZYLIDENE)-1H-INDEN-3-YLACETIC ACID
  • 5-Fluoro-2-methyl-1-[(Z)-[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid
  • (Z)-Sulindac sulfide
  • 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylthio)phenyl)methylene)-, (Z)-
  • Einecs 256-403-9
  • SULINDAC SULPHIDE
  • (Z)-5-FLUORO-2-METHYL-1-[P-(METHYLTHIO)BENZYLIDENE]INDENE-3-ACETIC ACID
CAS:
49627-27-2
MF:
C20H17FO2S
MW:
340.41
EINECS:
256-403-9
Product Categories:
  • Intermediates & Fine Chemicals
  • Metabolites
  • Pharmaceuticals
Mol File:
49627-27-2.mol
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SULINDAC SULFIDE Chemical Properties

Melting point:
189-191°C
storage temp. 
-20°C Freezer
solubility 
DMSO: >22 mg/mL
form 
solid
color 
yellow
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-42/43-63
WGK Germany 
3
HS Code 
2930902000

MSDS

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SULINDAC SULFIDE Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP.

Definition

ChEBI: An aryl sulfide that is a metabolite of sulindac. A non-steroidal anti-inflammatory drug, which also has anticancer activity.

SULINDAC SULFIDESupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Email
isunpharm@qq.com
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SULINDAC SULFIDE(49627-27-2)Related Product Information