3，7-dichloro-8-chloro methyl quinoline Chemical Properties

Boiling point:

348.3±37.0 °C(Predicted)

Density 

1.464±0.06 g/cm3(Predicted)

pka

0.04±0.42(Predicted)

3，7-dichloro-8-chloro methyl quinoline Usage And Synthesis

Chemical Properties

3，7-dichloro-8-chloro methyl quinoline is pure white crystal, mp129℃, soluble in organic solvents such as ethanol, benzene, chlorobenzene, dichlorobenzene, slightly soluble in petroleum ether, insoluble in water.

Uses

3,7-Dichloro-8-chloromethylquinoline is an intermediate of the herbicide quinclorac.

Synthesis

3，7-dichloro-8-chloro methyl quinoline's preparation method is to put 7-chloro-8-methylquinoline and o-dichlorobenzene in the reactor, and add catalyst azobisisobutyronitrile, heat up, pass chlorine gas, and control unreacted quinoline with gas chromatography, The content is less than or equal to 1%. Precipitation and recovery of o-dichlorobenzene give a mixture of 3,7-dichloro-8-chloromethylquinoline.