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Mesembrine

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Mesembrine Basic information

Product Name:
Mesembrine
Synonyms:
  • (3aS,7aβ)-1-Methyl-3aβ-(3,4-dimethoxyphenyl)octahydro-6H-indole-6-one
  • (7aβ)-1-Methyl-3aβ-(3,4-dimethoxyphenyl)octahydro-6H-indole-6-one
  • [3aS,7aβ,(-)]-3a-(3,4-Dimethoxyphenyl)octahydro-1-methyl-6H-indole-6-one
  • (-)-MeseMbranone
  • (3aS,7aS)-3a-(3,4-DiMethoxyphenyl)octahydro-1-Methyl-6H-indol-6-one
  • (3aS-cis)-3a-(3,4-DiMethoxyphenyl)octahydro-1- Methyl-6H-Indol-6-one
  • 4α,9α-MeseMbrine
  • MeseMbranone
CAS:
24880-43-1
MF:
C17H23NO3
MW:
289.36942
Product Categories:
  • Aromatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
24880-43-1.mol
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Mesembrine Chemical Properties

alpha 
D20 -55.4° (CH3OH)
Boiling point:
bp0.3 186-190°
Density 
1.133±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Chloroform: 10 mg/ml,Ethanol: 10 mg/ml
form 
Oil to Solid
pka
8.78±0.40(Predicted)
color 
Colourless to Light Yellow
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Mesembrine Usage And Synthesis

Uses

Mesembrine is an alkaloid used in preparing Channa, a drug of Southwest Africa. A serotonin-uptake inhibitor; occurs naturally as the (-)-form.

Definition

ChEBI: Mesembrine is a member of pyrrolidines.

Synthesis Reference(s)

Tetrahedron, 24, p. 6583, 1968 DOI: 10.1016/S0040-4020(01)96872-3

IC 50

Microbial Metabolite

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