6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-AMINE Chemical Properties

Boiling point:

450.4±45.0 °C(Predicted)

Density 

1.308±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO: 5 mg/mL (20.73 mM; ultrasonic and warming and heat to 80°C)

form 

Solid

pka

4.73±0.40(Predicted)

color 

Yellow to brown

6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-AMINE Usage And Synthesis

Uses

TIE-2/VEGFR-2 kinase-IN-1 is used for the synthesis of TIE-2 and/or VEGFR-2 inhibitors, extracted from patent WO2003022852, example 14. TIE-2/VEGFR-2 kinase-IN-1 is used for the study of diseases associated with inappropriate angiogenesis[1].

IC 50

Tie2

References

[1] Jerry Leroy Adams, et al. Furo-and thienopyrimidine derivatives as angiogenesis inhibitors. Patent WO2003022852.

6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-AMINE(453590-24-4)Related Product Information

• 2-(CHLOROMETHYL)-5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-AMINE
• 6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-AMINE
• 2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL
• Furo[2,3-d]pyrimidin-4-amine (9CI)
• AURORA 20150