R-(+)-COTININE
R-(+)-COTININE Basic information
- Product Name:
- R-(+)-COTININE
- Synonyms:
-
- R-(+)-COTININE
- (5R)-(+)-1-Methyl-5-(3-pyridiyl)-2-pyrrolidinone
- Ba 2701
- (R)-(+)-1-METHYL-5-(3-PYRIDIYL)-2-PYRROLIDINONE
- 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (5R)-
- CAS:
- 32162-64-4
- MF:
- C10H12N2O
- MW:
- 176.22
- Product Categories:
-
- Heterocycles
- Metabolites & Impurities
- Mutagenesis Research Chemicals
- Nicotine Derivatives
- Mol File:
- Mol File
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R-(+)-COTININE Chemical Properties
- Melting point:
- 48-51°C
- Boiling point:
- 145-150°C/3 mm
- Density
- 1.146±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.72±0.12(Predicted)
- color
- White to Off-White
- Stability:
- Moisture, Temperature Sensitive - Seal tightly, Store in Freezer, Hygroscopic
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R-(+)-COTININE Usage And Synthesis
Chemical Properties
Colourless to Light Brown Solid
Uses
The R metabolite of Nicotine. This is the unnatural isomer of Cotinine. Carcinogen.
in vivo
R-(+)-Cotinine (0.3-10 mg/kg; a single i.p.) enhances the effects of a subthreshold dose of Donepezil (0.5 mg/kg) on novel object recognition (NOR) performance[1].
R-(+)-COTININESupplier
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