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6,19-Dihydroxyurs-12-en-3-oxo-28-oic acid

Basic information Safety Supplier Related

6,19-Dihydroxyurs-12-en-3-oxo-28-oic acid Basic information

Product Name:
6,19-Dihydroxyurs-12-en-3-oxo-28-oic acid
Synonyms:
  • 6,19-Dihydroxyurs-12-en-3-oxo-28-oic acid
  • 6β,19-Dihydroxy-3-oxours-12-en-28-oic acid
  • (6alpha)-6,19-Dihydroxy-3-oxours-12-en-28-oic acid
  • Urs-12-en-28-oic acid, 6,19-dihydroxy-3-oxo-, (6α)-
  • 6β,19-Dihydroxy-3-oxours-12-en-28-oicacid
  • 19-Dihydroxy-3-oxours-12-en-28-oic acid
CAS:
194027-11-7
MF:
C30H46O5
MW:
486.68
Mol File:
194027-11-7.mol
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6,19-Dihydroxyurs-12-en-3-oxo-28-oic acid Chemical Properties

Boiling point:
616.9±55.0 °C(Predicted)
Density 
1.18±0.1 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
4.45±0.70(Predicted)
color 
White to off-white
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6,19-Dihydroxyurs-12-en-3-oxo-28-oic acid Usage And Synthesis

Uses

6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid (Compound 14) is an osteoclast inhibitor with anti-osteoclastogenic activity. 6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid can be obtained from Eriobotrya japonica leaves. 6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid can be used in osteoporosis research[1].

References

[1] Tan H, et al. A structure-activity relationship study on antiosteoclastogenesis effect of triterpenoids from the leaves of loquat (Eriobotrya japonica). Phytomedicine. 2015 Apr 15;22(4):498-503. DOI:10.1016/j.phymed.2015.03.002

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