ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > DNA damage > DNA / RNA Synthesis inhibitors > Triapine
Triapine
Triapine Basic information
- Product Name:
- Triapine
- Synonyms:
-
- 2-[(3-Amino-2-pyridinyl)methylene]hydrazinecarbothioamide
- Hydrazinecarbothioamide, 2-[(3-amino-2-pyridinyl)methylene]-, (2E)-
- Triapine USP/EP/BP
- (E)-3-AP
- (E)-2-((3-Aminopyridin-2-yl)methylene)hydrazinecarbothioamide
- CAS:
- 200933-27-3
- MF:
- C7H9N5S
- MW:
- 195.24
- Product Categories:
-
- Inhibitors
- Mol File:
- 200933-27-3.mol
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Triapine Chemical Properties
- Boiling point:
- 436.0±55.0 °C(Predicted)
- Density
- 1.46
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 10.93±0.70(Predicted)
- form
- Solid
- color
- Pale Yellow to Dark Beige
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Triapine Usage And Synthesis
Uses
Triapine is a potent ribonucleotide reductase inhibitor with broad spectrum anti-tumor activity.
Biological Activity
Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad-spectrum antitumor activity by inhibiting DNA synthesis.
target
Target | Value |
Ribonucleotide reductase |
TriapineSupplier
Shanghai Run-Biotech Co., Ltd.
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- 021-57171705 13817537615
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AdooQ Bioscience CHINA
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- 025-58849295 18951903616;
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Target molecule Corp.
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- 857-239-0968
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ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
- 2853530910@QQ.com
Amadis Chemical Company Limited
- Tel
- 571-89925085
- sales@amadischem.com