Z-PHE-LYS-2,4,6-TRIMETHYLBENZOYLOXY-METHYLKETONE TRIFLUOROACETATE SALT Chemical Properties

Boiling point:

809.6±65.0 °C(Predicted)

Density 

1.177±0.06 g/cm3(Predicted)

storage temp. 

-15°C

pka

11.07±0.46(Predicted)

Z-PHE-LYS-2,4,6-TRIMETHYLBENZOYLOXY-METHYLKETONE TRIFLUOROACETATE SALT Usage And Synthesis

Uses

Z-FK-ck (Z-Phe-Lys-2,4,6-Trimethylbenzoyloxy-methylketone) is a potent and selective gingipain-K-specific inhibitor. Z-FK-ck prolongs plasma thrombin time (TT) in a dose- and time-dependent manner[1].

References

[1] Imamura T, et, al. Effect of free and vesicle-bound cysteine proteinases of Porphyromonas gingivalis on plasma clot formation: implications for bleeding tendency at periodontitis sites. Infect Immun. 1995 Dec;63(12):4877-82. DOI:10.1128/iai.63.12.4877-4882.1995

Z-PHE-LYS-2,4,6-TRIMETHYLBENZOYLOXY-METHYLKETONE TRIFLUOROACETATE SALT(118253-05-7)Related Product Information

• ETHYL 2,4-DIMETHYLBENZOATE
• 2,6-Dimethylbenzoic acid
• Ethyl 2,4,6-trimethylbenzoate
• Z-PHE-LYS-2,4,6-TRIMETHYLBENZOYLOXY-METHYLKETONE TRIFLUOROACETATE SALT
• ETHYL 2,6-DIMETHYLBENZOATE
• Methyl 2,4,6-trimethylbenzoate
• 2,4,6-Trimethylbenzoic acid