8-PIPERIDINOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
8-PIPERIDINOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Basic information
- Product Name:
- 8-PIPERIDINOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
- Synonyms:
-
- 8-piperidinoadenosine-3’,5’-cyclicmonophosphorothioate,sp-isomer,(sp-8-pip-camps),sodiumsalt
- ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-PIPERIDINO-, SP-ISOMER, SODIUM SALT
- 8-PIPERIDINOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
- SP-8-PIP-CAMPS, NA
- SP-8-PIP-CAMPS SODIUM SALT
- 8-Piperidinoadenosine-3'',5''-cyclic monophosphothioate sodium salt Sp isomer
- Adenosine, 8-(1-piperidinyl)-, cyclic 3',5'-[hydrogen [P(S)]-phosphorothioate]
- Sp-8-PIP-cAMPS
- CAS:
- 156816-35-2
- MF:
- C15H21N6O5PS
- MW:
- 428.4
- Mol File:
- 156816-35-2.mol
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8-PIPERIDINOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Chemical Properties
- Boiling point:
- 696.3±65.0 °C(Predicted)
- Density
- 2.06±0.1 g/cm3(Predicted)
- pka
- -0.55±0.60(Predicted)
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8-PIPERIDINOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Usage And Synthesis
Uses
Sp-8-PIP cAMP sodium is a non-corresponding isomer of 8-Piperidino-cAMP. 8-Piperidino-cAMP binds with high affinity to site A of the regulatory subunit of cAMP-dependent protein kinase type I (AI). Sp-8-PIP cAMP sodium can be used as an antagonist of cAMP-induced activation[1].
References
[1] Ogreid D, et al. (Rp)- and (Sp)-8-piperidino-adenosine 3',5'-(cyclic)thiophosphates discriminate completely between site A and B of the regulatory subunits of cAMP-dependent protein kinase type I and II. Eur J Biochem. 1994 May 1;221(3):1089-94. DOI:10.1111/j.1432-1033.1994.tb18828.x
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