Basic information Safety Supplier Related

N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester

Basic information Safety Supplier Related

N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester Basic information

Product Name:
N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester
Synonyms:
  • Alanine, N-[3-fluoro-4-[(MethylaMino)carbonyl]phenyl]-2-Methyl-, Methyl ester
  • Methyl 2-((3-fluoro-4-(MethylcarbaMoyl)phenyl)aMino)-2-Methylpropanoate
  • N-[3-fluoro-4-[(MethylaMino)carbonyl]phenyl]-2-Methyl-Alanine Methyl ester 2-(3-Fluoro-4-MethylcarbaMoyl-phenylaMino)-2-Methyl-propionic acid Methyl ester "
  • N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester
  • 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate methyl
  • NN-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester
  • methyl 2-[3-fluoro-4-(methylcarbamoyl)anilino]-2-methyl-propanoat e
  • Enzalutamide Impurity 32
CAS:
1332524-01-2
MF:
C13H17FN2O3
MW:
268.28
Mol File:
1332524-01-2.mol
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N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester Chemical Properties

Boiling point:
381℃
Density 
1.203
Flash point:
184℃
storage temp. 
Storage temp. 2-8°C
solubility 
Chloroform, DCM, Ethyl Acetate
pka
14.35±0.46(Predicted)
form 
Solid
color 
White
InChI
InChI=1S/C13H17FN2O3/c1-13(2,12(18)19-4)16-8-5-6-9(10(14)7-8)11(17)15-3/h5-7,16H,1-4H3,(H,15,17)
InChIKey
MLHUTKWFDCMHQO-UHFFFAOYSA-N
SMILES
C(OC)(=O)[C@](C)(C)NC1=CC=C(C(NC)=O)C(F)=C1
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N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester Usage And Synthesis

Uses

N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine Methyl Ester is an intermediate in the synthesis of MDV 3100 (M199800), is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex.

N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl esterSupplier

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