Galloflavin Chemical Properties

Melting point:

>140°C (dec.)

Boiling point:

727.6±60.0 °C(Predicted)

Density 

2.10±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMSO: soluble5mg/mL, clear

pka

6.75±0.20(Predicted)

form 

powder

color 

light yellow to light brown

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

WGK Germany 

3

Galloflavin Usage And Synthesis

Uses

Galloflavin is a novel inhibitor of lactate dehydrogenase and is a potential anticancer agent. This compound is suitable for lactate dehydrogenase (LDH) related research.

Biochem/physiol Actions

Galloflavin is an inhibitor of lactate dehydrogenase (LDH). The compound blocks both isoforms of (LDH-A and –B) with Ki values of 5.5 and 15 μM, respectively. Inhibition of the glycolytic pathway by galloflavin induces oxidative stress and apoptosis in breast tumor cell lines.