BMS-791325
BMS-791325 Basic information
- Product Name:
- BMS-791325
- Synonyms:
-
- BMS-791325 HCl
- Beclabuvir HCl
- BMS-791325 1G
- BMS-791325 Beclabuvir hydrochloride
- BMS-791325
- Beclabuvir hydrochloride
- BMS 791325 hydrochloride
- BMS 791325-08
- CAS:
- 958002-36-3
- MF:
- C36H46ClN5O5S
- MW:
- 696.3
- Mol File:
- 958002-36-3.mol
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BMS-791325 Usage And Synthesis
Enzyme inhibitor
This potent allosteric inhibitor (FW = 673.87 g/mol) targets hepatitis C virus NS5B polymerase IC50 <0.5 nM (biochemical assay) and EC50 = 0.8-6 nM (replicon assay). Unlike prior cyclopropyl-fused indolobenzazepine inhibitors, BMS-791325 has improved solubility and membrane permeability properties as well as reduced off-target activities, directed most notably against human pregnane X receptor (hPXR) transactivation.
BMS-791325Supplier
BeiJing Hwrk Chemicals Limted
- Tel
- 0757-86329057 18934348241
- sales4.gd@hwrkchemical.com
Taizhou Crene Biotechnology Co., Ltd.
- Tel
- 0576-88813233 88205808
- sales@taizhoukerui.com
Pharmacodia (Beijing) Co.,Ltd
- Tel
- +86-400-851-9921
- sales@pharmacodia.com
Shanghai QianYan Bio-technology Co., Ltd
- Tel
- 02781293128
- orders@biochemsafebuy.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 17754423994 17754423994
- 2853530910@QQ.com