PP2 analog
PP2 analog Basic information
- Product Name:
- PP2 analog
- Synonyms:
-
- PP2 analog
- PP 2 ANALOG;PP-2 ANALOG
- 5-(4-Chlorophenyl)-7-(1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-(4-chlorophenyl)-7-(1,1-dimethylethyl)-
- CHEMBL 306012
- CHEMBL306012
- CHEMBL-306012
- CAS:
- 309739-67-1
- MF:
- C16H17ClN4
- MW:
- 300.79
- Mol File:
- 309739-67-1.mol
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PP2 analog Chemical Properties
- Boiling point:
- 499.9±45.0 °C(Predicted)
- Density
- 1.28±0.1 g/cm3(Predicted)
- pka
- 5.53±0.30(Predicted)
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PP2 analog Usage And Synthesis
Uses
PP2 Analog (compound 3) is a ATP-competitive Src family kinases inhibitor with the IC50 values of 0.22, 0.15, 2.68, and 7 aganist of lck (64-509), src , kdr, and tie-2[1].
References
[1] Arnold LD, et al. Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck I. Bioorg Med Chem Lett. 2000;10(19):2167-2170. DOI:10.1016/s0960-894x(00)00441-8
PP2 analogSupplier
Shanghai Boyle Chemical Co., Ltd.
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- sales@boylechem.com
EnliPharma Technology Co., Ltd
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- 0551-66399836 18955197623
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Shanghai joygo pharmacetical tech., Co., Ltd.
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- 13621615409
- sale1@joygooo.com
Shanghai YuanYe Biotechnology Co., Ltd.
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- 021-61312847; 18021002903
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Medi-tech Bioscientific Co., Ltd.
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- 0519-83246372 13585352506