4'-ACETYL-N-[4-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]BUTYL]-[1,1'-BIPHENYL]-4-CARBOXAMIDE
4'-ACETYL-N-[4-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]BUTYL]-[1,1'-BIPHENYL]-4-CARBOXAMIDE Basic information
- Product Name:
- 4'-ACETYL-N-[4-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]BUTYL]-[1,1'-BIPHENYL]-4-CARBOXAMIDE
- Synonyms:
-
- 4'-ACETYL-N-[4-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]BUTYL]-[1,1'-BIPHENYL]-4-CARBOXAMIDE
- GR 103691
- 4'-acetyl-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-[1,1'-biphenyl]-4-carboxamide
- [1,1'-Biphenyl]-4-carboxamide, 4'-acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-
- Inhibitor,GR-103691,GR 103691,GR103691,Dopamine Receptor,inhibit
- 4'-Acetyl-N-[4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl]-[1,1'-biphenyl]-4-carboxaMide
- 4'-Acetyl-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-[1,1'-biphenyl]-4-carboxamide
- CAS:
- 162408-66-4
- MF:
- C30H35N3O3
- MW:
- 485.62
- Mol File:
- 162408-66-4.mol
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4'-ACETYL-N-[4-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]BUTYL]-[1,1'-BIPHENYL]-4-CARBOXAMIDE Chemical Properties
- Density
- 1.132
- storage temp.
- 2-8°C
- solubility
- DMSO: ~9 mg/mL at 60 °C, soluble
- form
- solid
- color
- white
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
MSDS
- Language:English Provider:SigmaAldrich
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4'-ACETYL-N-[4-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]BUTYL]-[1,1'-BIPHENYL]-4-CARBOXAMIDE Usage And Synthesis
Uses
GR 103691 is a potent and selective receptor antagonist for D3DR.
Definition
ChEBI: 4-(4-acetylphenyl)-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]benzamide is an aromatic ketone.
Biological Activity
A potent and selective dopamine D 3 receptor antagonist, with a K i value of 0.3 nM? and > 100- fold selectivity over D 2 and D 4 sites.
4'-ACETYL-N-[4-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]BUTYL]-[1,1'-BIPHENYL]-4-CARBOXAMIDESupplier
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