2',3'-Bis-(O-t-butyldimethylsilyl)uridine
2',3'-Bis-(O-t-butyldimethylsilyl)uridine Basic information
- Product Name:
- 2',3'-Bis-(O-t-butyldimethylsilyl)uridine
- Synonyms:
-
- 2',3'-Bis-(O-t-butyldimethylsilyl)uridine
- Uridine, 2',3'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-
- 2',3'-Bis-O-tert-butyldimethylsilyluridine
- 2’,3’-Bis-(O-t-butyldimethyl silyl) uridine
- CAS:
- 69504-12-7
- MF:
- C21H40N2O6Si2
- MW:
- 472.72
- Mol File:
- 69504-12-7.mol
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2',3'-Bis-(O-t-butyldimethylsilyl)uridine Usage And Synthesis
Uses
2’,3’-Bis-(O-t-butyldimethylsilyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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