N1-Methyl-2'-deoxyadenosine Chemical Properties

Boiling point:

609.7±65.0 °C(Predicted)

Density 

1.74±0.1 g/cm3(Predicted)

pka

13.88±0.60(Predicted)

form 

Solid

color 

White to off-white

N1-Methyl-2'-deoxyadenosine Usage And Synthesis

Uses

N1-Methyl-2'-deoxyadenosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005