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methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride

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methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride Basic information

Product Name:
methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride
Synonyms:
  • methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride
  • (R)-METHYL 2-AMINO-3-(7-METHYL-1H-INDAZOL-5-YL)PROPANOATE 2HCL
  • (R)-Methyl 2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride
  • Methyl (R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride
  • 1H-Indazole-5-propanoic acid, α-amino-7-methyl-, methyl ester, hydrochloride (1:2), (αR)-
CAS:
1414976-14-9
MF:
C12H16ClN3O2
MW:
269.73
Mol File:
1414976-14-9.mol
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methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride Chemical Properties

InChI
InChI=1/C12H15N3O2.ClH/c1-7-3-8(5-10(13)12(16)17-2)4-9-6-14-15-11(7)9;/h3-4,6,10H,5,13H2,1-2H3,(H,14,15);1H/t10-;/s3
InChIKey
FNDDCJUEQKEEQV-MEQOOBBNNA-N
SMILES
CC1C=C(C[C@@H](N)C(=O)OC)C=C2C=NNC=12.Cl |&1:5,r|
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methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride Usage And Synthesis

Uses

Methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride is a crucial intermediate of Zavegepant. It contains a single chiral centre, whose formation is catalyzed by a transaminase.

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