TRIAZAMATE Chemical Properties

Melting point:

60°

Boiling point:

280°C (rough estimate)

Density 

1.2357 (rough estimate)

vapor pressure 

1.6 x l0^-4 Pa (25 °C)

refractive index 

1.6200 (estimate)

Flash point:

189℃

pka

0.48±0.50(Predicted)

Water Solubility 

433 mg l^-1(25 °C)

BRN 

8422595

EPA Substance Registry System

Triazamate (112143-82-5)

Safety Information

Hazard Codes 

T,N

Risk Statements 

23-25-36-50

Safety Statements 

26-45-61

RIDADR 

UN2811 - class 6.1 - PG 2 - EHS - Toxic solids, organic, n.o.s., HI: all

WGK Germany 

3

Toxicity

LD50 (14 d) in mice, rats (mg/kg): 61, 50-200 orally; in rats (mg/kg): >5000 dermally (Murray); LC50 (48 h) in daphnia: 0.048 mg/l; (96 h) in bluegill, trout: 1.0, 0.43 mg/l (Murray)

TRIAZAMATE Usage And Synthesis

Uses

Triazamate is used for the control of aphids by foliar application on a wide variety of crops. It is suitable for inclusion in integrated pest management because it is minimally toxic to beneficial insects.

Uses

Triazamate is used in controlling unpleasant pests.Used in preparation of Thiazole Manganese Zinc compounds and compounds thereof.

Uses

Pesticide.

Definition

ChEBI: A triazole insecticide that is 1H-1,2,4-triazole which is substituted at positions 1, 3, and 5 by N,N-dimethylaminocarbonyl, tert-butyl, and (2-ethoxy-2-oxoethyl)sulfanediyl groups, resp ctively.

General Description

Triazamate is a carbamoyl triazole compound, widely used as an insecticide and its mode of action involves the inhibition of cholinesterase in insect pests.

Metabolic pathway

There is only a limited amount of information on the fate of triazamate currently in the public domain. Metabolism in sugar beet and apple has been reported. Animal metabolism studies have been conducted but details are not available. Triazamate is very rapidly metabolised by hydrolysis, decarbamoylation and further metabolism in all biological systems studied (PM).

Degradation

Triazamate is stable under normal conditions and in solution at pH 7 and below. Its DT₅₀ values in buffers are, at pH 5, 7 and 9, 220 days, 49 hours and 1 hour, respectively (PM). Base-catalysed hydrolysis should initially afford triazamate acid (2) by carboxyl ester cleavage (see Scheme 1).
The DTM of triazamate on aqueous photolysis at pH 7 is 301 days (PM)

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