N-(Azido-PEG3)-N-Fluorescein-PEG4-acid Usage And Synthesis

Biological Activity

N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

N-(Azido-PEG3)-N-Fluorescein-PEG4-acid(2100306-72-5)Related Product Information

• Fluorescein-PEG4-Acid
• Fluorescein-PEG6-Acid
• N-(Azido-PEG3)-N-Fluorescein-PEG3-acid
• 5-FITC-PEG3-azide
• N-(Azido-PEG2)-N-Fluorescein-PEG3-acid