N-Mal-N-bis(PEG2-acid) Chemical Properties

Boiling point:

721.5±60.0 °C(Predicted)

Density 

1.319±0.06 g/cm3(Predicted)

solubility 

Soluble in Water, DMSO, DCM, DMF

pka

3.97±0.10(Predicted)

N-Mal-N-bis(PEG2-acid) Usage And Synthesis

Description

N-Mal-N-bis(PEG2-acid) is a thiol reactive PEG reagent. Maleimide reacts specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The terminal carboxylic acids can react with primary amino groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.