Basic information Safety Supplier Related

[2-(2-Chloro-ethoxy)-ethoxy]-acetic acid tert-butyl ester

Basic information Safety Supplier Related

[2-(2-Chloro-ethoxy)-ethoxy]-acetic acid tert-butyl ester Basic information

Product Name:
[2-(2-Chloro-ethoxy)-ethoxy]-acetic acid tert-butyl ester
Synonyms:
  • tert-butyl 2-(2-(2-chloroethoxy)ethoxy)acetate
  • [2-(2-Chloro-ethoxy)-ethoxy]-acetic acid tert-butyl ester
  • Chloro-PEG2-t-butyl acetate
  • Acetic acid, 2-[2-(2-chloroethoxy)ethoxy]-, 1,1-dimethylethyl ester
  • Chloro-PEG2-Boc
  • 2-(2-(2-Chloro-ethoxy)ethoxy)acetic acid tert-butyl ester
CAS:
1442085-43-9
MF:
C10H19ClO4
MW:
238.71
Mol File:
1442085-43-9.mol
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[2-(2-Chloro-ethoxy)-ethoxy]-acetic acid tert-butyl ester Chemical Properties

Boiling point:
301.2±22.0 °C(Predicted)
Density 
1.078±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Liquid
color 
Light yellow to yellow
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[2-(2-Chloro-ethoxy)-ethoxy]-acetic acid tert-butyl ester Usage And Synthesis

Uses

Chloro-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

[2-(2-Chloro-ethoxy)-ethoxy]-acetic acid tert-butyl esterSupplier

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