PG-9 MALEATE Chemical Properties

storage temp. 

Store at RT

solubility 

Soluble to 100 mM in DMSO

form 

Powder

PG-9 MALEATE Usage And Synthesis

Uses

PG 9 maleate is a compound with analgesic and anti-memory loss activity. PG 9 maleate exerts analgesic effects by enhancing central cholinergic transmission. PG 9 maleate protects against memory loss caused by scopolamine or dicyclomine within a specific dose range. The affinity profile of PG 9 maleate indicates significant selectivity among the M4/M1 receptor subtypes, which may be the mechanism for its analgesic and anti-memory loss effects. PG 9 maleate can increase the release of acetylcholine, thereby improving its biological activity[1].

References

[1] Antinociceptive and antiamnesic properties of the presynaptic cholinergic amplifier PG-9 PMID:9495837