1,3-DIOXANE Chemical Properties

Melting point:

-45 °C (lit.)

Boiling point:

105-106 °C (lit.)

Density 

1.032 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.418(lit.)

Flash point:

59 °F

storage temp. 

Flammables area

form 

clear liquid

color 

Colorless to Almost colorless

Water Solubility 

Fully miscible in water.

BRN 

102532

Stability:

Stable. Flammable. Incompatible with oxidizing agents. May form explosive peroxides in contact with the air - store under inert gas.

EPA Substance Registry System

1,3-Dioxane (505-22-6)

Safety Information

Hazard Codes 

F,Xn

Risk Statements 

11-20/21/22

Safety Statements 

16

RIDADR 

UN 1165 3/PG 2

WGK Germany 

3

RTECS 

JG8224000

HS Code 

2932.99.9090

HazardClass 

3.1

PackingGroup 

II

Hazardous Substances Data

505-22-6(Hazardous Substances Data)

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

1,3-DIOXANE Usage And Synthesis

Chemical Properties

colourless liquid

Uses

1,3-Dioxane has been employed as solvent in the synthesis of 8- and 9-membered dioxazocines and dioxazonines.

Definition

ChEBI: 1,3-dioxane is a dioxane and a cyclic acetal.

Preparation

1,3-dioxane is prepared by the reaction of formaldehyde and 1,3-propanediol in the presence of Br?nsted or Lewis acid catalysts.

General Description

Clear colorless liquid.

Air & Water Reactions

Highly flammable. Can form dangerous peroxides when exposed to air. Water soluble.

Reactivity Profile

1,3-DIOXANE is sensitive to heat. 1,3-DIOXANE can react with oxidizers.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 1,3-DIOXANE emits acrid smoke and fumes.

Fire Hazard

1,3-DIOXANE is flammable.

Purification Methods

Dry the dioxane with sodium and fractionally distil it. [Beilstein 19/1 V 11.]

1,3-DIOXANE(505-22-6)Related Product Information

• 1,3-Dioxan-2-one
• 2-(2-Bromoethyl)-1,3-dioxane
• 2,4,8,10-TETRAOXASPIRO[5.5]UNDECANE
• 3,9-Divinyl-2,4,8,10-tetraoxaspiro[5.5]undecane
• 2,2-Dimethyl-1,3-dioxane-4,6-dione
• 5,5-DIMETHYL-1,3-DIOXAN-2-ONE
• 4-PHENYL-1,3-DIOXANE
• 1,3-DIOXANE
• 2,2,5-Trimethyl-1,3-dioxane-4,6-dione
• 2-(1,3-Dioxan-2-yl)ethyltriphenylphosphonium bromide
• 1,4-Cyclohexanedione mono(2,2-dimethyltrimethylene ketal)
• 2,2-DIMETHYL-5-PHENYL-1,3-DIOXANE-4,6-DIONE
• Glycerol formal
• 4-METHYL-1,3-DIOXANE
• 4,6-O-Ethylidene-alpha-D-glucose
• METHYL 4,6-O-BENZYLIDENE-ALPHA-D-GLUCOPYRANOSIDE
• 1,2:3,5-Di-O-isopropylidene-alpha-D-xylofuranose
• 1-(1,4-Benzodioxane-2-carbonyl)piperazine