N-Boc-O-(2-azidoethyl)-L-tyrosine Chemical Properties

storage temp. 

Store at 0-8 °C

Appearance

colorless liquid or white solid

N-Boc-O-(2-azidoethyl)-L-tyrosine Usage And Synthesis

Uses

Boc-L-Tyr(2-azidoethyl)-OH (N-Boc-O-(2-azidoethyl)-L-tyrosine) is a click chemistry reagent containing an azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

References

[1] Xin BT, et, al. Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits. J Med Chem. 2019 Feb 14;62(3):1626-1642. DOI:10.1021/acs.jmedchem.8b01884