Pyrrole-2-carboxylic acid Chemical Properties

Melting point:

204-208 °C (dec.) (lit.)

Boiling point:

340.3±15.0 °C(Predicted)

Density 

0.862

refractive index 

1.441-1.445

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Soluble in methanol.

form 

Powder

pka

4.45(at 20℃)

color 

White to off-white to pale pink

BRN 

80825

CAS DataBase Reference

634-97-9(CAS DataBase Reference)

NIST Chemistry Reference

Pyrrole-2-carboxylic acid(634-97-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Pyrrole-2-carboxylic acid Usage And Synthesis

Chemical Properties

Light brown powder

Uses

Pyrrole-2-carboxylic acid is small amphoteric polar metabolite produced by many Streptomyces species, often co-produced with its dimer, pyrocoll. Pyrrole-2-carboxylic acid is an important dereplication standard in discovery, displaying a distinctive UV spectrum and a broad range of biological activities, albeit weak. More recently, pyrrole-2-carboxylic has demonstrated antiparasitic activity against Trypanosomes by selective proline racemase inhibition and has potent antifungal activity against Phytophthora.

Uses

Pyrrole-2-carboxylic Acid is a reagent used in the synthesis of potent small molecule inhibitors of severe acute respiratory syndrome (SARS) coronavirus. Also used in the synthesis of [2,3-c]pyridine-7-one scaffolds.

Definition

ChEBI: A pyrrolecarboxylic acid that is 1H-pyrrole carrying a carboxy substituent at position 2.

Pyrrole-2-carboxylic acid(634-97-9)Related Product Information

• Pyrrole-2-carboxaldehyde
• Ethyl 2-(Chlorosulfonyl)acetate
• Pyrrole
• Polyvinylpyrrolidone
• N-Methyl-2-pyrrolidone
• Povidone iodine
• Pyrrolidine
• N-Vinyl-2-pyrrolidone
• Ethyl pyrrole-2-carboxylate
• (1H-PYRROL-2-YL)-ACETIC ACID
• PYRROLIDINE-1-SULFONYL CHLORIDE
• 1H-PYRROLE-1-PROPANOIC ACID
• Pyrrole-3-carboxaldehyde
• (1H-PYRROL-2-YL)-ACETONITRILE
• Pyrrole-3-carboxylic acid
• Pyrrole-3-carboxylic acid
• Methyl 2-pyrrolecarboxylate
• PYRROLE-2-CARBONITRILE