Basic information Safety Supplier Related

5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE

Basic information Safety Supplier Related

5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE Basic information

Product Name:
5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE
Synonyms:
  • 1-(5-BROMO-2-HYDROXY-3-NITROPHENYL)ETHANONE
  • 3-BROMO-6-HYDROXY-5-NITRO ACETOPHENONE
  • 5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE
  • 5-BROMO-2-HYDROXY-3-NITROACETOPHENONE
  • JRH-01018, 1-(5-Bromo-2-hydroxy-3-nitrophenyl)ethanone, 97%
  • 5'-Bromo-2'-hydroxy-3'-nitroacetophenone >
  • Ethanone, 1-(5-bromo-2-hydroxy-3-nitrophenyl)-
  • 1-(5-Bromo-2-hydroxy-3-nitrophenyl)ethan-1-one
CAS:
70978-54-0
MF:
C8H6BrNO4
MW:
260.04
Product Categories:
  • Aromatic Acetophenones & Derivatives (substituted)
  • Building Blocks
  • C7 to C8
  • Carbonyl Compounds
  • Chemical Synthesis
  • Ketones
  • Organic Building Blocks
Mol File:
70978-54-0.mol
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5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE Chemical Properties

Melting point:
129-132 °C(lit.)
Boiling point:
272.9℃
Density 
1.763
Flash point:
118.9℃
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
6.47±0.38(Predicted)
color 
Light yellow to Yellow to Orange
CAS DataBase Reference
70978-54-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29145090

MSDS

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5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE Usage And Synthesis

Uses

5'-Bromo-2'-hydroxy-3'-nitroacetophenone is used as a chemical reagent in the synthesis of amides and benzoxazoles directly using a sulfate catalyst and microwaves. 1-(5-Bromo-2-hydroxy-3-nitrophen yl)ethanone is used in studies involving HIV-1 integrase inhibitors.

Preparation

Preparation by nitration of 5-bromo-2-hydroxyacetophenone in refluxing carbon tetrachloride (88%).

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