L-Thyroxine-13C9,15N
L-Thyroxine-13C9,15N Basic information
- Product Name:
- L-Thyroxine-13C9,15N
- Synonyms:
-
- L-Thyroxine-13C9,15N
- Levothyroxine-13C9-15N
- Thyroxine Carboxy,α,β,1,2,3,4,5,6-13C9,15N
- O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine-carboxy,α,β,1,2,3,4,5,6-13C9-15N
- CAS:
- 1431868-11-9
- MF:
- C15H11I4NO4
- MW:
- 786.96002
- Mol File:
- 1431868-11-9.mol
L-Thyroxine-13C9,15N Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMF: 0.14 mg/ml; DMSO: 2.5 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml
- form
- A solid
L-Thyroxine-13C9,15N Usage And Synthesis
Description
L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine. In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse model of hypothyroidism. Formulations containing L-thyroxine have been used in the treatment of hypothyroidism.
Uses
Thyroxine Carboxy,α,β,1,2,3,4,5,6-13C9,15N is 13C and 15N labeled analogue of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis.
L-Thyroxine-13C9,15NSupplier
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L-Thyroxine-13C9,15N(1431868-11-9)Related Product Information
- Levothyroxine Impurity
- (2S,2''S)-3,3''-(((6,6''-Dihydroxy-5-iodo-[1,1''-biphenyl]-3,3''-diyl)bis(oxy))bis(3,5-diiodo-4,1-phenylene))bis(2-aminopropanoic Acid)
- Levothyroxine Impurity 12
- Levothyroxine Impurity 16
- Levothyroxine EP Impurity B
- Levothyroxine Related Compound (2-Acetamido-3-(4-acetoxy-3,5-diiodophenyl)propanoic Acid)
- 3-Iodo-DL-tyrosine
- 3,5-DIIODOTHYROACETIC ACID
- Levothyroxine Impurity
- Levosimendan Impurity 8
- Levothyroxine Impurity 54
- Levothyroxine Impurity
- Levothyroxine Related Compound (2-Acetamido-3-(3,5-diiodo-4-(4-methoxyphenoxy)phenyl) Propanoic Acid)
- 3,3',5-TRIIODOTHYROPROPIONIC ACID
- Levothyroxine Impurity 16
- (S)-2-(2-Amino-3-(4-(3,5-diiodo-4-methoxyphenoxy)-3,5-diiodophenyl)propanamido)acetic Acid
- α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide
- Levothyroxine Impurity