ceramide NP Chemical Properties

Boiling point:

722℃ at 101.325kPa

Density 

0.982 at 20℃

vapor pressure 

0Pa at 25℃

pka

13.65±0.20(Predicted)

form 

Solid

color 

White to off-white

InChIKey

ATGQXSBKTQANOH-UWVGARPKSA-N

SMILES

C(N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC)(=O)CCCCCCC/C=C\CCCCCCCC

LogP

11.79 at 25℃ and pH7

ceramide NP Usage And Synthesis

Uses

Ceramide 3B is a ceramide 3 lipid class with aggregation behavior. Ceramide 3B has a variety of physiological functions and can serve as a penetration enhancer and auxiliary emulsifier, playing an important role in barrier function stability[1][2].

Definition

ChEBI: N-oleoylphytosphingosine is a phytoceramide in which the N-acyl group is specified as oleoyl (9Z-octadecenoyl). It is functionally related to an oleic acid.

References

[1] De Paepe K, et al. Incorporation of ceramide 3B in dermatocosmetic emulsions: effect on the transepidermal water loss of sodium lauryl sulphate-damaged skin. J Eur Acad Dermatol Venereol. 2000 Jul;14(4):272-9. DOI:10.1046/j.1468-3083.2000.00103.x
[2] Garidel P, et al. Aggregation behaviour of ceramide class 3 lipids[J]. HASYLAB Annual Report, 2003, 1: 1009-1010.