H-TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
H-TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2 Basic information
- Product Name:
- H-TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
- Synonyms:
-
- YHKTDSFVGLM-NH2
- (TYR0)-NEUROKININ A
- TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
- H-TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
- TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2: YHKTDSFVGLM-NH2
- L-Methioninamide, L-tyrosyl-L-histidyl-L-lysyl-L-threonyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valylglycyl-L-leucyl- (9CI)
- Kassinin,1-de-L-aspartic acid-2-L-tyrosine-3-L-histidine-5-L-threonine-7-L-serine-
- CAS:
- 116868-93-0
- MF:
- C59H89N15O16S
- MW:
- 1296.49
- Product Categories:
-
- peptide
- Mol File:
- Mol File
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H-TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2 Chemical Properties
- Boiling point:
- 1739.9±65.0 °C(Predicted)
- Density
- 1.319±0.06 g/cm3(Predicted)
- storage temp.
- -15°C
- pka
- 4.17±0.10(Predicted)
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H-TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2 Usage And Synthesis
Uses
Tyr0-Neurokinin A is a neuropeptide belongs to tachykinin peptide family. Tyr0-Neurokinin A is an agonist of Tacr2. Tyr0-Neurokinin A can be used in the research of insulin resistance, obesity, diabetes[1][2].
References
[1] Gao X, et al. The study of the conformation and interaction of two tachykinin peptides in membrane mimicking systems by NMR spectroscopy and pulsed field gradient diffusion. Biopolymers. 1999 Oct 15;50(5):555-68. DOI:10.1002/(SICI)1097-0282(19991015)50:5<555::AID-BIP9>3.0.CO;2-X
[2] Gerhart-Hines Zachary, et al. Peptide agonists of Tacr2 for treatment of insulin resistance, diabetes and/or obesity. Patent. WO2021073742.
H-TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2Supplier
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H-TYR-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2(116868-93-0)Related Product Information
- (TYR0)-C-TYPE NATRIURETIC PEPTIDE (32-53) (HUMAN, PORCINE, RAT)
- (TYR0)-KALIURETIC PEPTIDE (HUMAN)
- (TYR0)-FIBRINOPEPTIDE A
- H-TYR-ALA-VAL-SER-GLU-HIS-GLN-LEU-LEU-HIS-ASP-LYS-GLY-LYS-SER-ILE-GLN-ASP-LEU-ARG-ARG-ARG-PHE-PHE-LEU-HIS-HIS-LEU-ILE-ALA-GLU-ILE-HIS-THR-ALA-GLU-ILE-ARG-ALA-THR-SER-OH
- [TYR0] GASTRIC INHIBITORY PEPTIDE (23-42), HUMAN
- (TYR0)-HYPERCALCEMIA OF MALIGNANCY FACTOR (1-34) (HUMAN, RAT)
- (TYR0)-STRESSCOPIN-RELATED PEPTIDE (HUMAN)
- (TYR0)-UROCORTIN (RAT)
- (TYR0)-STRESSCOPIN (HUMAN)
- H-TYR-ASP-MET-HIS-ASP-PHE-PHE-VAL-GLY-LEU-MET-NH2