ER-27319 Chemical Properties

Melting point:

135 - 137°C

storage temp. 

2-8°C

solubility 

DMSO: 28 mg/mL

form 

solid

color 

Pale Yellow to Light Yellow

Safety Information

Hazard Codes 

Xn

Risk Statements 

21/22

Safety Statements 

24/25

WGK Germany 

1

ER-27319 Usage And Synthesis

Uses

ER 27319 Maleate is a PLK-1 and Syk inhibitor.

Biological Activity

Selective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of Fc ε RI in rat and human mast cells. Results in the abrogation of degranulation, TNF- α production (IC 50 = 10 μ M) and other related signaling events.

ER-27319(201010-95-9)Related Product Information

• Ethanone, 1-(2-amino-3,4-dimethylphenyl)- (9CI)
• ER-27319