2-(2-aminoethyl)phenol Chemical Properties

Melting point:

113-115 °C

Boiling point:

258.0±15.0 °C(Predicted)

Density 

1.103±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

9.41±0.35(Predicted)

2-(2-aminoethyl)phenol Usage And Synthesis

Description

2-Hydroxyphenethylamine (also known as phenylethanolamine) is a kind of trace amine found in the brain. It may modulate the sympathetic functions. It has strong cardiovascular activity, and can be used as a drug to produce topical vasoconstriction. Its derivatives are adrenergic agonists and antagonists, and have the potential for the treatment of respiratory diseases.

Uses

A ortho-hydroxylated phenylethylamine present in urine of patients with affective disorder following (MAO-inhibiting) antidepressant drug treatment. It has been used in studies as a substrate of monoamine oxidase B and was revealed to be a potential inactivator of MAO-B.

Uses

2-(2-aminoethyl)phenol is a ortho-hydroxylated phenylethylamine present in urine of patients with affective disorder following (MAO-inhibiting) antidepressant drug treatment. It has been used in studies as a substrate of monoa mine oxidase B and was revealed to be a potential inactivator of MAO-B.

Definition

ChEBI: 2-(2-aminoethyl)phenol is a primary amine.

Synthesis Reference(s)

The Journal of Organic Chemistry, 41, p. 2502, 1976 DOI: 10.1021/jo00876a038

References

https://en.wikipedia.org/wiki/Phenylethanolamine
Biggadike, Keith, et al. "PHENYLETHANOLAMINE DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES." WO, EP 1556340 A1. 2005.
https://pubchem.ncbi.nlm.nih.gov/compound/2-Amino-1-phenylethanol#section=Top

2-(2-aminoethyl)phenol (2039-66-9)Related Product Information

• 2-Nitrodiphenylamine
• DL-O-TYROSINE
• Midodrine hydrochloride
• 2-ETHOXYPHENETHYLAMINE
• cularine
• 6-HYDROXYDOPAMINE HYDROCHLORIDE
• METHOXAMINE HYDROCHLORIDE
• oxidopamine
• 6-HYDROXYDOPAMINE HYDROBROMIDE
• 2-Methoxyphenethylamine
• 2,5-Dimethoxyphenethylamine hydrochloride
• N,N-Dimethyl-p-hydroxyphenethylamine
• b-Hydroxyphenethylamine.,DL-B-HYDROXYPHENETHYLAMINE,(±)-β-Hydroxyphenethylamin
• Tyramine hydrochloride
• 3-Methoxy-4-Hydroxyphenethylamine HCl,3-Methoxy-4-hydroxyphenethylamine hydrochloride, 3-MT, 4-(2-Aminoethyl)-2-methoxyphenol hydrochloride
• Tyramine
• 3,4-methylenedioxy-alpha,N-dimethyl-N-hydroxyphenethylamine
• 3-Methoxy-4-hydroxyphenethylamine