DIBENZOFURAN-4-CARBOXYLIC ACID Chemical Properties

Melting point:

211-215 °C(lit.)

Boiling point:

425.7±18.0 °C(Predicted)

Density 

1.387±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 1 mg/ml

form 

solid

pka

3.24±0.30(Predicted)

color 

White to light yellow

InChI

InChI=1S/C13H8O3/c14-13(15)10-6-3-5-9-8-4-1-2-7-11(8)16-12(9)10/h1-7H,(H,14,15)

InChIKey

BSMAWCXKHJSJIB-UHFFFAOYSA-N

SMILES

O1C2=CC=CC=C2C2=CC=CC(C(O)=O)=C12

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

DIBENZOFURAN-4-CARBOXYLIC ACID Usage And Synthesis

Uses

4-Dibenzofurancarboxylic acid is one of the synthesis materials of polycyclic aromatic hydrocarbons (PAHs) and Schistosoma mansoni histone deacetylase 8 (smHDAC8) inhibitors[1][2].

References

[1] Ghazy E, et al. Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis. Eur J Med Chem. 2021 Dec 5;225:113745. DOI:10.1016/j.ejmech.2021.113745
[2] Molotkov AP, et al. Effect of Cp-Ligand Methylation on Rhodium(III)-Catalyzed Annulations of Aromatic Carboxylic Acids with Alkynes: Synthesis of Isocoumarins and PAHs for Organic Light-Emitting Devices. Chempluschem. 2020 Feb;85(2):334-345. DOI:10.1002/cplu.202000048

DIBENZOFURAN-4-CARBOXYLIC ACID(2786-05-2)Related Product Information

• DIBENZOFURAN-4-CARBOXALDEHYDE 97
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• dibenzofuran-4-ol
• methyl dibenzo[b,d]furan-4-carboxylate
• Dibenzofuran-3-carboxylic acid
• Dibenzofuran-2-carboxylic acid
• benzofuran-7-carboxylic acid
• 4-METHYLDIBENZOFURAN
• 7-Benzofurancarboxaldehyde (9CI)
• DIBENZOFURAN-4-CARBOXYLIC ACID
• 7-methylbenzofuran
• Dibenzofuran