2-Hydroxynicotinaldehyde Chemical Properties

Melting point:

220-222°

Boiling point:

50 °C(Press: 80 Torr)

Density 

1.365±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

form 

powder or crystals

pka

10.18±0.10(Predicted)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36

Safety Statements 

26-24/25

HazardClass 

IRRITANT

HS Code 

29333990

2-Hydroxynicotinaldehyde Usage And Synthesis

Uses

This reagent was used as a catalytic transient directing group by Jin-Quan Yu′s lab for Pd(II)-catalyzed γ-C(sp³)-H arylation to couple free primary amines with aryl iodides. Reactions included Pd(OAc)₂ 683124 and low catalyst and directing group loading.

2-Hydroxynicotinaldehyde(36404-89-4)Related Product Information

• 2-Hydroxy-6-methylpyridine-3-carboxylic acid
• 1-AZAXANTHONE
• 2-(4-METHYLPHENOXY)NICOTINIC ACID
• 2-PHENOXYNICOTINIC ACID
• 2-(4-CHLOROPHENOXY)NICOTINIC ACID
• 2-Hydroxynicotinic acid
• 2-HYDROXY-4-PYRIDINECARBOXALDEHYDE
• 3-Hydroxypyridine-2-carboxaldehyde
• 6-HYDROXYNICOTINALDEHYDE,6-HYDROXYNICOTINALDEHYDE (6-HYDROXY-3-PYRIDINE CARBOXYALDEHYDE)
• 3-Pyridinecarboxaldehyde
• 2-(4-CHLOROPHENOXY)NICOTINAMIDE
• 2-(4-METHYLPHENOXY)NICOTINAMIDE
• 1-(3,4-DICHLOROBENZYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXYLIC ACID
• 1-(2,6-DICHLOROBENZYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXYLIC ACID
• 2-PHENOXYNICOTINAMIDE
• 1-(2,6-DICHLOROBENZYL)-N,N-DIMETHYL-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE
• 1-(3,4-DICHLOROBENZYL)-2-OXO-N-PHENYL-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE
• N-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-1-(3,4-DICHLOROBENZYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE