(Z)-3-[(AMINOIMINOMETHYL)THIO]PROP-2-ENOIC ACID SULFATE Chemical Properties

Melting point:

164 °C (decomp)

Boiling point:

314.3±44.0 °C(Predicted)

Density 

1.47±0.1 g/cm3(Predicted)

storage temp. 

Store at RT

form 

White solid.

pka

2.43±0.25(Predicted)

(Z)-3-[(AMINOIMINOMETHYL)THIO]PROP-2-ENOIC ACID SULFATE Usage And Synthesis

Uses

ZAPA Sulfate, is an agonist at low affinity GABAA receptors, and can be used in the study of GABA receptors linked to benzodiazepine receptors.

Definition

ChEBI: An imidothiocarbamic ester that is (2Z)-prop-2-enoic acid with a carbamimidoylsulfanyl group at position 3.

Biological Activity

More potent than either GABA or muscimol as an agonist at low affinity GABA A receptors and is thus a useful ligand to investigate GABA receptors linked to benzodiazepine receptors. Also a GABA C receptor antagonist.

(Z)-3-[(AMINOIMINOMETHYL)THIO]PROP-2-ENOIC ACID SULFATE(92138-10-8)Related Product Information

• (Z)-3-[(AMINOIMINOMETHYL)THIO]PROP-2-ENOIC ACID SULFATE
• ETHYL 1-(2-ETHOXY-2-OXOETHYL)-4-({5-[(Z)-2-METHOXY-2-OXOETHYLIDENE]-4-OXO-3-PHENYL-1,3-THIAZOLIDIN-2-YLIDENE}AMINO)-1H-IMIDAZOLE-5-CARBOXYLATE
• METHYL (2Z)-[(2Z)-3-(2-METHOXYETHYL)-2-(PHENYLIMINO)-4-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE]ACETATE
• ETHYL 4-{[(2Z,5Z)-5-(2-METHOXY-2-OXOETHYLIDENE)-4-OXO-3-PHENYL-1,3-THIAZOLIDIN-2-YLIDENE]AMINO}-1H-IMIDAZOLE-5-CARBOXYLATE
• METHYL (2Z)-((2Z)-2-{[(4-METHYL-1,2,3-THIADIAZOL-5-YL)CARBONYL]HYDRAZONO}-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)ACETATE
• (2Z)-[2-[5-HYDROXY-3-(2-NAPHTHYL)-5-(TRIFLUOROMETHYL)-4,5-DIHYDRO-1H-PYRAZOL-1-YL]-4-OXO-1,3-THIAZOL-5(4H)-YLIDENE]ACETIC ACID
• ETHYL 4-({5-[(Z)-2-METHOXY-2-OXOETHYLIDENE]-4-OXO-3-PHENYL-1,3-THIAZOLIDIN-2-YLIDENE}AMINO)-1-(2-OXOPROPYL)-1H-IMIDAZOLE-5-CARBOXYLATE
• METHYL (2Z)-{(2Z)-4-OXO-2-[(PYRIDIN-3-YLCARBONYL)HYDRAZONO]-1,3-THIAZOLIDIN-5-YLIDENE}ACETATE
• METHYL (2Z)-((2Z)-2-{[(5-NITRO-1H-IMIDAZOL-4-YL)CARBONYL]HYDRAZONO}-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)ACETATE
• METHYL (2Z)-[(2Z)-2-({5-[(METHYLAMINO)CARBONYL]-1H-IMIDAZOL-4-YL}IMINO)-4-OXO-3-PHENYL-1,3-THIAZOLIDIN-5-YLIDENE]ACETATE
• METHYL (2Z)-[(2Z)-2-(ETHYLIMINO)-3-(4-METHYLPHENYL)-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE]ACETATE
• METHYL (2Z)-[(2Z)-3-(4-METHOXYPHENYL)-4-OXO-2-(PHENYLIMINO)-1,3-THIAZOLIDIN-5-YLIDENE]ACETATE
• METHYL (2Z)-[(2Z)-2-(ETHYLIMINO)-3-(4-FLUOROPHENYL)-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE]ACETATE
• METHYL (2Z)-[(2Z)-3-(2-METHOXYETHYL)-4-OXO-2-(PHENYLIMINO)-1,3-THIAZOLIDIN-5-YLIDENE]ACETATE
• METHYL (2Z)-((2Z)-2-{[5-(AMINOCARBONYL)-1H-IMIDAZOL-4-YL]IMINO}-4-OXO-3-PHENYL-1,3-THIAZOLIDIN-5-YLIDENE)ACETATE
• ETHYL (2Z)-{(2E)-2-[(2E)-(2,3-DIHYDROXYBENZYLIDENE)HYDRAZONO]-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE}ACETATE
• METHYL (2Z)-[(2Z)-3-BENZYL-4-OXO-2-(PHENYLIMINO)-1,3-THIAZOLIDIN-5-YLIDENE]ACETATE
• METHYL (2Z)-[(2Z)-3-(3,4-DIMETHYLPHENYL)-2-(ETHYLIMINO)-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE]ACETATE