L-759,656
L-759,656 Basic information
- Product Name:
- L-759,656
- Synonyms:
-
- L-759,656
- (6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,8,9,10,10a-hexahydro-1-methoxy-6,6-dimethyl-9-methylene-6H-dibenzo[b,d]pyran
- 656
- 6H-Dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,8,9,10,10a-hexahydro-1-methoxy-6,6-dimethyl-9-methylene-, (6aR,10aR)-
- CAS:
- 174627-56-6
- MF:
- C26H40O2
- MW:
- 384.59
- Mol File:
- 174627-56-6.mol
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L-759,656 Chemical Properties
- Boiling point:
- 448.3±45.0 °C(Predicted)
- Density
- 0.99±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
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L-759,656 Usage And Synthesis
Uses
L-759,656 is a potent CB2-selective annabinoid receptor antagnoist.
Biological Activity
Highly selective CB 2 receptor agonist (K i values are 11.8 and 4888 nM for CB 2 and CB 1 receptors respectively). Potently inhibits forskolin-stimulated cAMP production via CB 2 receptors expressed in CHO cells (EC 50 = 3.1 nM).