4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1-(1,1-dimethylethyl) ester
4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1-(1,1-dimethylethyl) ester Basic information
- Product Name:
- 4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1-(1,1-dimethylethyl) ester
- Synonyms:
-
- 4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1-(1,1-dimethylethyl) ester
- Acid-PEG7-t-butyl ester
- HOOCCH2CH2O-PEG6-CH2CH2COOtBu
- Acid-PEG7-t-Bu Ester
- HOOCCH2CH2O-PEG6-CH2CH2COOtBu/4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1-(1,1-dimethylethyl) ester
- 2,2-Dimethyl-4-oxo-3,7,10,13,16,19,22,25-octaoxaoctacosan-28-oic acid
- CAS:
- 2134235-86-0
- MF:
- C22H42O11
- MW:
- 482.56
- Mol File:
- 2134235-86-0.mol
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4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1-(1,1-dimethylethyl) ester Chemical Properties
- Boiling point:
- 561.1±50.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- pka
- 4.28±0.10(Predicted)
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4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1-(1,1-dimethylethyl) ester Usage And Synthesis
Uses
Acid-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277
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