chlorbenzoxamine
chlorbenzoxamine Basic information
- Product Name:
- chlorbenzoxamine
- Synonyms:
-
- 1-[2-[(2-Chlorophenyl)phenylmethoxy]ethyl]-4-[(2-methylphenyl)methyl]piperazine
- Chlorbenzoxyethamine
- Chlorobenzoxamine
- chlorbenzoxamine
- Piperazine, 1-[2-[(2-chlorophenyl)phenylmethoxy]ethyl]-4-[(2-methylphenyl)methyl]-
- CAS:
- 522-18-9
- MF:
- C27H31ClN2O
- MW:
- 435
- EINECS:
- 208-323-0
- Mol File:
- 522-18-9.mol
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chlorbenzoxamine Chemical Properties
- Boiling point:
- bp0.01 234-236°; bp0.005 235°
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chlorbenzoxamine Usage And Synthesis
Originator
Chlorbenzoxamine,Shanghai
Definition
ChEBI: Chlorbenzoxamine is a diarylmethane.
Manufacturing Process
A mixture of 0.1 mol of 1-m-methylbenzyl-4-(2-hydroxyethyl)-piperazine and 0.1 mol of o-chlorobenzhydrile chloride was heated at 160°C for 3 hours. After cooling the product obtained was dissolved in benzene. The solution was washed with 20% aqueous solution of sodium carbonate and then with water. Chlorbenzoxamine was distilled in vacuo, B.P. 240°C/0.1 mm Hg. Yield 50%.
Therapeutic Function
Anticholinergic, Antiulcer