suclofenide
suclofenide Basic information
- Product Name:
- suclofenide
- Synonyms:
-
- suclofenide
- 3-Chloro-4-(3-phenyl-2,5-dioxopyrrolidin-1-yl)benzenesulfonamide
- 3-chloro-4-(2,5-dioxo-3-phenylpyrrolidin-1-yl)benzenesulfonamide
- Benzenesulfonamide, 3-chloro-4-(2,5-dioxo-3-phenyl-1-pyrrolidinyl)-
- Neosulfalepsine
- PB385
- Benzoicacid,3,4,6-tris(phenylmethoxy)-
- CAS:
- 30279-49-3
- MF:
- C16H13ClN2O4S
- MW:
- 364.8
- EINECS:
- 2501115
- Mol File:
- 30279-49-3.mol
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suclofenide Chemical Properties
- Melting point:
- 205-207°
- Boiling point:
- 677.1±65.0 °C(Predicted)
- Density
- 1.507±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 9.56±0.60(Predicted)
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suclofenide Usage And Synthesis
Uses
Suclofenide (Neosulfalepsine; PB385) is an anticonvulsant that affects GABA metabolism.
Definition
ChEBI: Suclofenide is a member of pyrrolidines.
References
[1] Sibler E F. Beeinflussung des GABA-Metabolismus durch das Antiepileptikum Sulfalepsin (PB 385)[D]. ETH Zurich, 1985.
[2] Mikes F, et al. 3-Chloro-4-(phenylsuccinimido)-benzenesulfonamide (GS 385), a new anticonvulsant: its quantitative determination, pharmacokinetics and metabolism using high performance liquid chromatography. Arzneimittelforschung. 1979;29(10):1583-8.
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