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2,5-dihydroxybenzenesulphonic acid

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2,5-dihydroxybenzenesulphonic acid Basic information

Product Name:
2,5-dihydroxybenzenesulphonic acid
Synonyms:
  • 2,5-dihydroxybenzenesulphonic acid
  • EINECS 201-833-4
  • Dobesilate
  • Hydroquinonesulfonic Acid (Dobesilic Acid)
  • Benzenesulfonic acid, 2,5-dihydroxy-
  • Dobesilic Acid
  • Calcium Dobesilate Impurity 22
CAS:
88-46-0
MF:
C6H6O5S
MW:
190.17
EINECS:
201-833-4
Mol File:
88-46-0.mol
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2,5-dihydroxybenzenesulphonic acid Chemical Properties

Density 
1.743±0.06 g/cm3(Predicted)
pka
-0.51±0.30(Predicted)
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2,5-dihydroxybenzenesulphonic acid Usage And Synthesis

Originator

Dicynone,Delalande,France,1965

Uses

Isopropyl Quinonesulfonate is a derivative of Sodium quinonesulfonate(51579-78-3), and an impurity of Calcium Dobesilate (C145100).

Definition

ChEBI: A dihydroxybenzenesulfonic acid that is hydroquinone in which one of the phenyl hydrogens is substituted by a sulfonic acid group.

Manufacturing Process

163 grams of pure diethylamine bisulfite are added to an ethyl alcohol solution of 108 grams of 1,4-benzoquinone at a temperature not above 5°C and under continuous stirring. After reaction, the alcohol is removed by distilling under vacuum. The product is recrystallized from ethyl alcohol at 80°C. Yield: 198 grams of diethylammonium cyclohexadienol 4-one-1- sulfonate-4. MP 125°C.

Therapeutic Function

Hemostatic

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