arfendazam
arfendazam Basic information
- Product Name:
- arfendazam
- Synonyms:
-
- arfendazam
- 7-Chloro-2,3,4,5-tetrahydro-4-oxo-5-phenyl-1H-1,5-benzodiazepine-1-carboxylic acid ethyl ester
- 7-Chloro-4-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-1-carboxylic acid ethyl ester
- 1H-1,5-Benzodiazepine-1-carboxylic acid, 7-chloro-2,3,4,5-tetrahydro-4-oxo-5-phenyl-, ethyl ester
- Ethyl 7-chloro-4-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-1-carboxylate
- CAS:
- 37669-57-1
- MF:
- C18H17ClN2O3
- MW:
- 344.79
- EINECS:
- 2535830
- Mol File:
- 37669-57-1.mol
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arfendazam Usage And Synthesis
Originator
Arfendazam,ZYF Pharm Chemical
Manufacturing Process
A phosgene was mixed with ethanol, then cooling by ice-water the solution of 8-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2-one in chloroform was added dropwise, mixed and allowed to stand. Then the reaction mixture was concentrated, and crystals was filtered off. So the 7- chloro-2,3,4,5-tetrahydro-4-oxo-5-phenyl-1H-1,5-benzodiazepine-1-carboxylic acid ethyl ester was obtained, melting point 172°-173°C (dec.).
Therapeutic Function
Tranquilizer