11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate)
11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate) Basic information
- Product Name:
- 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate)
- Synonyms:
-
- 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate)
- Prednisolone phosphate
- Prednisolone 21-phosphate
- 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-phosphoric acid
- 11β,17-Dihydroxy-21-(phosphonooxy)pregna-1,4-diene-3,20-dione
- PSLP
- [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] dihydrogen phosphate
- [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] dihydrogen phosphate
- CAS:
- 302-25-0
- MF:
- C21H29O8P
- MW:
- 440.42
- EINECS:
- 2061201
- Mol File:
- 302-25-0.mol
11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate) Usage And Synthesis
Uses
Glucocorticoid.
Uses
11,17-dihydroxy-21-(phosphonooxy)-Pregna-1,4-diene-3,20-dione is a steroid.
Definition
ChEBI: Prednisolone phosphate is a synthetic glucocorticoid resulting from the formal condensation of the 21-hydroxy group of prednisolone with one of the hydroxy groups of phosphoric acid. It is a prodrug for prednisolone that is activated in vivo by phosphatases. It has a role as an anti-inflammatory agent, a glucocorticoid receptor agonist, a prodrug and an antineoplastic agent. It is a steroid phosphate, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a tertiary alpha-hydroxy ketone and a glucocorticoid. It is functionally related to a prednisolone. It is a conjugate acid of a prednisolone phosphate(2-).
brand name
Hydeltrasol (Merck); Inflamase (Novartis); Metreton (Schering); Orapred (BioMarin); Pediapred (UCB); Predair (Pharmafair).